The event focused on technologies for integrated, human-based 3D systems—ranging from organoids to organ-on-a-chip. The focus was on essential components in the areas of the brain, heart, and gut, disease models, cancer research, and drug screening. The speakers’ presentations each highlighted specific technological areas and introduced workshop participants to current methods and developments. In doing so, they provided deep insights into the precision microfabrication of complex tissue and barrier models, the further development of bioinks and biofabricated constructs, as well as the latest microfluidic platforms—featuring valves, perfusion, and controlled microenvironments. The range of topics was complemented by smart materials for membranes, scaffolds, and soft actuation; highly automated systems for sample and high-throughput applications; and embedded sensor technology and micro- and nanoelectronics for the precise measurement of electrical, optical, and chemical signals. AI-based imaging pipelines combine data acquisition, analysis, and automated feedback, thereby enabling fully integrated experiments and representing a third focus of GENESIS 26.